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NETSCC manages five distinct but interconnected evaluation research programmes, on behalf of, and operating within the context of the wider NIHR.

Efficacy and Mechanism Evaluation (EME) Programme
NIHR Health Services and Delivery Research (HS&DR) Programme
NIHR Health Technology Assessment (HTA) Programme
NIHR Public Health Research (PHR) Programme
NIHR Systematic Reviews (SR) Programme


Efficacy and Mechanism Evaluation (EME) Programme

The EME Programme evaluates research into the clinical efficacy of an intervention, where proof of concept in humans has already been achieved, and may add significantly to our understanding of biological or behavioural mechanisms and processes. The EME Programme is funded by the MRC and NIHR, with contributions from the CSO in Scotland and NISCHR in Wales and the HSC R&D Division, Public Health Agency in Northern Ireland. It is managed by the NIHR Evaluation, Trials and Studies Coordinating Centre (NETSCC) based at the University of Southampton. . continue

NIHR Health Services and Delivery Research (HS&DR) Programme

The HS&DR programme aims to produce rigorous and relevant evidence on the quality, access and organisation of health services, including costs and outcomes. The programme enhances the strategic focus on research that matters to the NHS including research on implementation and a range of knowledge mobilisation initiatives. It is keen to support ambitious evaluative research to improve health services.  continue

NIHR Health Technology Assessment (HTA) Programme

The HTA Programme delivers research information about the effectiveness, costs and broader impact of healthcare treatments and tests for those who plan, provide or receive care in the NHS.

The HTA Programme commissions and funds research via four different routes:

  • Standard calls -  commissions research proposals that address specific topics or themes; 
  • HTA Clinical evaluation and trials calls - invites research proposals for evaluation studies and clinical trials on topics proposed directly by researchers;
  • Themed calls  - one-off invitations for proposals to fund research in areas where a particular need has been identified;
  • Technology Assessment Report (TAR) contract - specialist assessment centres are contracted by the Department of Health to undertake technology assessment reports on behalf of the National Institute for Health and Clinical Excellence (NICE) and other policy customers.  continue

NIHR Public Health Research (PHR) Programme

The PHR programme evaluates public health interventions, providing new knowledge on the benefits, costs, acceptability and wider impacts of non-NHS interventions intended to improve the health of the public and reduce inequalities in health.  continue

NIHR Systematic Reviews (SR) Programme

It is widely accepted that the findings of individual research studies are rarely sufficient to justify new treatments. Systematic reviews identify, evaluate, combine and summarise the findings of all relevant individual studies and, when carried out well, provide decision makers with the best possible information about the effects of tests, treatments and other interventions used in health and social care. NETSCC provides strategic oversight and manages the contracts for the Systematic Reviews Programme on behalf of the NIHR. continue

Do you know which programme you need to go to?

yesthen go directly to the programme website or to the webpage for the relevant theme:

Within the distinct remits, each programme may fund research within the common themes of: technology evaluation, public health and health services organisation.


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The NIHR Evaluation, Trials and Studies Coordinating Centre (NETSCC), based at the University of Southampton, manages evaluation research programmes and activities for the NIHR.


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