This page has moved to our new website. Please wait to be redirected automatically, or click here to go directly.

NETSCC - Logo

NIHR Clinical Trials Units Support Funding

Quicklinks
 Impact and achievements
 Apply now to join our panels and boards
 Health Services and Delivery Research Programme
 NIHR Antimicrobial Resistance Themed Call
 Calls for proposals - all NETSCC programmes
 NETSCC is part of NIHR www.nihr.ac.uk
Latest News
 Clinical trial reports need improving, says NETSCC advisor
 Does exercising more improve the treatment of depression?
 National Institute for Health Research to make debut at British Science Festival with live trial
 Opportunity to tender - Coordinating Centre for the NIHR Clinical Research Network
 NIHR HTA Conference: What’s in it for you?
 

rss NETSCC News Feeds
twitter icon Follow NIHR on Twitter

 

 you are here › HomeNIHR Trials Overview NIHR Clinical Trials Units Support Funding

The NIHR recognises the important and crucial role played by Clinical Trials Units (CTUs) in helping to deliver quality research projects.

“Clinical Trials Units are central to our vision of expanding clinical trials in the country.” (Professor Dame Sally Davies, Director General of Research and Development, Department of Health)

NIHR CTU Support Funding is intended to strengthen the capacity for designing and conducting clinical trials and other evaluation studies. It does this by providing funding to offer additional stability and flexibility, and giving units increased capacity to support applications and projects.

Please see the FAQ section below for further information.

FAQ
1. What is NIHR CTU Support Funding?
2. How is funding awarded?
3. How does CTU Support Funding work?
4. Can I view a list of current award holders?
5. Who sits on the CTU Standing Advisory Committee? 

Links
For more information on current registered CTUs and the registration process please visit the UKCRC Clinical Trials Units website.

How to contact us
In the first instance please contact nihrctu@southampton.ac.uk


FAQs

Q. What is NIHR CTU Support Funding?

A . NIHR CTU Support Funding was introduced by the NIHR in 2008 to strengthen the capacity for conducting clinical trials within the NHS, and for delivery of the quality research projects required by the NIHR. This initiative was part of the NIHR and MRC joint health research strategy. CTU Support Funding is intended to provide additional stability and flexibility, allowing units to increase capacity to support research funding applications and projects.

Q. How is funding awarded?

A . All CTUs in England that are registered with the UKCRC, either fully or provisionally are eligible to apply. Applications are reviewed by the NIHR CTU Standing Advisory Committee. Membership of the committee can be found here. All units are assessed on their track record, their planned use of the award and their ability to attract appropriate levels of NIHR programme research funding to be off set against the funding award.

Once funded CTUs are evaluated annually to determine:

  • if the unit is being active in supporting an appropriate level of funding applications to NIHR programmes, funded NIHR trials and other evaluation studies, and is maintaining a suitable NIHR programme portfolio to generate an offset*
  • whether the funding band is appropriate for the activity levels and performance reported
  • whether the offset* (reimbursement) level to be applied to future payments is appropriate
  • if the funding is being used appropriately against stated objectives.

* Please see How does CTU Support Funding work for an explanation of the offset model and requirements.

A copy of the public minutes can be viewed by clicking the links below:

December 2012 NIHR CTU Standing Advisory Committee public minutes

December 2011 NETS CTU Standing Advisory Committee public minutes

December 2010 NETS CTU Standing Advisory Committee public minutes

Q. How does CTU Support Funding work?

A . The award is intended for use as ‘priming' funds, to support the CTU by increasing ability to offer longer contracts to staff and increase research capacity. The expected result of this investment is an increase in the number of high quality research applications submitted to NIHR programmes and supported projects. It is not core-funding.

The intention is that CTU Support Funding awards will be made on an institutional basis. In Higher Education Institutions (HEIs) or NHS Trusts where there is more than one unit it is expected that units will collaborate in a consortium arrangement.

CTU Support Funding payments are offset against the income from successful NIHR programme project grants. The idea is that once the CTU is stabilised by an increase in grant income, the amount of CTU Support Funding will be reduced. All projects that started or had funding agreed since the start of a CTU's Support Funding award will be eligible for offset. On receipt and review of the annual report, a reduction will then be calculated (as appropriate) in the next payments made to the CTU; seeking to reclaim a maximum of 80% of the total CTU Support Funding Award, but never more than equivalent 50% of income earned from each eligible project.

For Example:
Unit X receives £200,000 per annum CTU Support Funding (£100K paid every 6 months).
Last year they received £271,024 in eligible income for work on two HTA trials.
We do not want to take more than 50% of the income they have received from each project - 50% of £271,024 is £135,512.
80% of their £200K SF award is £160K - as £135,512 does not exceed this we would reclaim all of the £135,512.
The difference being a permanent contribution to CTU capacity building, retained by the unit.
The money to be reclaimed would be split equally over the following two payments - £67,576 less each payment.
Resulting payments will be £34,424 in April and £32,424 in October.

The maximum offset limit is 80% of the CTU Support Funding awarded; if units achieve in excess of this level offset, the money to be reclaimed would be capped at 80% of what they had been awarded.

For example:
Unit X receives £200,000 per annum CTU Support Funding (£100K paid every 6 months).
Last year they received £458,046 in eligible income for work on one EME & three HTA trials.
We do not want to take more than 50% of the income they have received from each project - 50% of £458,046 is £229,023.
£229,023 is equivalent to 114.5% of their Support Funding award. As this exceeds the 80%, we would reclaim only 80% of their Support Funding award of £200,000, which is £160,000.
The money to be reclaimed would be split equally over the following two payments - £80,000 less each payment.
Resulting payments will be £20,000 in April and £20,000 in October.

Q. Can I view a list of current award holders?

A . A list of the CTUs receiving CTU Support Funding, with direct links to their websites, can be found below.

Clinical Trials Unit

Host Organisation

Birmingham Clinical Trials Unit

University of Birmingham

Bristol Randomised Trials Collaboration

University of Bristol

Cambridge Clinical Trials Unit Cambridge University Hospitals NHS

Imperial Clinical Trials Unit

Imperial College London

ICNARC

Intensive Care National Audit and Research Centre

Kings Clinical Trials Unit

Kings College London

Leeds Clinical Trials Research Unit

University of Leeds

Leicester Clinical Trials Unit

University of Leicester

Liverpool Clinical Trials Collaborative University of Liverpool

London School of Hygiene & Tropical Medicine Clinical Trials Unit

London School of Hygiene &
Tropical Medicine

Manchester Academic Health Science Centre, Trials Coordination Unit

The Christie NHS Foundation Trust

National Perinatal Epidemiology Unit (NPEU) Clinical Trials Unit

University of Oxford

Newcastle Clinical Trials Unit

Newcastle University

Norwich Clinical Research & Trials Unit

Norfolk and Norwich University
Hospital

Nottingham Clinical Trials Unit

University of Nottingham

Oxford Clinical Trials

University of Oxford

Peninsula Clinical Trials Unit

Peninsula Medical School

Pragmatic Clinical Trials Unit

Barts and The London School of
Medicine and Dentistry

PRIMENT Clinical Trials Unit

University College London

Sheffield Clinical Trials Research Unit

University of Sheffield

The Keele Primary Care Musculoskeletal Trials Unit

Keele University

University of Southampton Clinical Trials Unit

University of Southampton

Warwick Clinical Trials Unit

University of Warwick

York Trials Unit

University of York

 

Q. Who sits on the NIHR CTU Standing Advisory Committee?

A. Membership of the NIHR CTU Standing Advisory Committee (as of September 2012):

Chair

Professor Tom Walley, Director of NETS, University of Liverpool

Members

Professor Deborah Ashby, Imperial College London
Professor Julia M Brown , University of Leeds
Professor Simon Gates, University of Warwick
Professor Jenny Hewison, University of Leeds
Professor Sallie Lamb, University of Oxford
Professor Max Parmar, MRC Clinical Trials Unit
Professor Jon Nicholl, University of Sheffield
Professor Tim Peters, University of Bristol
Professor David Torgerson, University of York

 printer friendly version

The NIHR Evaluation, Trials and Studies Coordinating Centre (NETSCC), based at the University of Southampton, manages evaluation research programmes and activities for the NIHR.

 

University of Southampton - Logo